Golden State standouts Klay Thompson and Draymond Green both missed the contest due to right knee injuries.

Deandre Ayton registered 25 points and 11 rebounds and Scoot Henderson had 18 points and 12 assists for Portland (21-59), which lost for the 13th time in the past 15 games. Jabari Walker added 17 points and 16 rebounds, and Kris Murray scored 14 points.

Portland shot 36.1 percent from the field, including a meager 8 of 34 (23.5 percent) from 3-point range. Henderson committed nine turnovers, giving him 17 over the past two games.

Kevon Looney collected 11 rebounds for Golden State, which shot 46.8 percent from the field and 12 of 35 (34.3 percent) from 3-point range. The Warriors swept the four-game season series with Portland and have won 10 of the past 11 meetings.

The Trail Blazers led 85-79 after a 3-pointer by Murray with 9:09 left in the game before going 6:37 without a field goal.

Golden State responded with a 16-1 run. Curry tied the score at 86 by sinking a 17-footer with 6:25 remaining, and Looney split two free throws to give the Warriors the lead with 5:06 left.

Curry knocked down a 3-pointer to make it 90-86 with 4:42 to play and fed Looney for a layup to make it a six-point margin with 3:26 remaining. Brandin Podziemski converted a three-point play to increase the lead to 95-86 with 3:03 left.

Ayton’s basket with 2:32 to go ended Portland’s field-goal drought after nine consecutive misses.

Chris Paul’s trey made it 100-90 with 1:04 remaining as Golden State closed it out.

Curry and Kuminga scored 11 points apiece as Golden State led 49-46 at the break. Ayton had 15 in the half for Portland.

The Warriors held a 75-74 edge entering the fourth quarter.